Anti-EXO1 Antibody

This unconjugated rabbit polyclonal primary antibody from Antibodies.com targets EXO1 (Exonuclease 1), a 5' to 3' exonuclease with central roles in eukaryotic mismatch repair, DNA double-strand break resection, and meiotic recombination. Raised in rabbit and purified as a polyclonal IgG preparation, the reagent is supplied as a 50 µl liquid aliquot and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples. The antibody recognizes the full-length EXO1 protein, which runs near 94 kDa on SDS-PAGE, supporting band detection in WB and cytoplasmic or nuclear localization studies in IHC and IF. Researchers studying microsatellite instability in colorectal and endometrial tumors, as well as DNA damage response pathways, recombination mechanisms, and replication fork processing, use this reagent to probe EXO1 expression and recruitment to repair foci.