Anti-EWSR1 Antibody

The EWSR1 protein (Ewing Sarcoma Breakpoint Region 1) is a multifunctional RNA-binding nuclear factor encoded on chromosome 22q12. From the Antibodies.com catalogue, this rabbit polyclonal reagent targets the multi-domain N-terminal portion of EWSR1 and is supplied as 200 µL of unconjugated IgG in a stabilizing buffer. Validated for Western blot and immunofluorescence workflows on human and mouse samples, the antibody enables researchers to study native EWSR1 expression, subcellular localization, and the downstream consequences of chromosomal rearrangements that drive Ewing sarcoma, myxoid liposarcoma, desmoplastic small round cell tumor, clear cell sarcoma, and other translocation-positive neoplasms. Because a polyclonal reagent recognizes multiple epitopes across the target, it provides broader coverage than a monoclonal alternative, which is useful when probing fixed or denatured tissue in IF experiments and total lysates in WB. The unconjugated format allows the user to pair the antibody with their preferred secondary detection chemistry, including HRP, fluorophore, or biotin conjugates depending on the experimental read-out. Aliquot on receipt and store frozen to minimize freeze-thaw cycles.