Anti-ETV4 Antibody

ETV4 (ETS Variant Transcription Factor 4), also known as PEA3 or E1AF, is a nuclear transcription factor of the PEA3 subfamily of ETS proteins. This unconjugated polyclonal reagent from Antibodies.com is raised in rabbit and validated for western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples.

ETV4 regulates genes involved in cell proliferation, migration, and differentiation, and its aberrant expression has been documented in prostate, breast, and gastric carcinomas, where it contributes to epithelial-mesenchymal transition and metastatic spread. Developmental biology groups also rely on ETV4 detection to map neural crest patterning and organogenesis in vertebrate models, while neuroscience research has linked the factor to motor neuron connectivity.

Each vial is supplied at 100 µl of polyclonal antiserum intended for research use only. For best results, aliquot upon arrival and store refrigerated; avoid repeated freeze-thaw cycles to preserve antibody titer. The unconjugated format allows flexible pairing with custom fluorophores, HRP, or biotin conjugates depending on the assay design.