Anti-ETV4 Antibody

ETV4 (ETS Variant Transcription Factor 4), also known as PEA3 or E1AF, is a member of the ETS family of transcription factors implicated in embryonic development, cell migration, and oncogenic signaling across multiple tissue types. This rabbit polyclonal antibody from Antibodies.com is raised against ETV4 and supplied as an unconjugated reagent at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial. Validated for Western blot, immunohistochemistry, and immunofluorescence workflows, the antibody cross-reacts with Human, Mouse, and Rat samples, supporting translational research where cross-species comparison is needed. Researchers commonly deploy this reagent to probe ETV4 expression in tumor microenvironments, prostate and breast cancer models, and developmental tissue sections, where its nuclear localization aids in visualizing transcription factor distribution. The polyclonal format increases the likelihood of recognizing multiple epitopes on the ETV4 protein, which can be advantageous when working with partially degraded lysates or when signal robustness is a priority over strict epitope-specific detection.