Anti-Estrogen Receptor-a (Ab-106) Antibody

Offered by Antibodies.com, this affinity-purified reagent is a Rabbit polyclonal antibody raised against the Ab-106 epitope of human Estrogen Receptor-α (ESR1), generated by immunizing rabbits with a synthetic peptide corresponding to amino acids 104–108 (S-P-S-P-L) and isolated by epitope-specific affinity chromatography. The antibody is supplied as an unconjugated, liquid formulation at a concentration of 1.0 mg/mL in phosphate-buffered saline (without Mg²⁺ and Ca²⁺), pH 7.4, containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol. The catalog unit ships at 4 °C in a 50 µL volume (a 100 µL format is also listed) and should be aliquoted upon arrival and stored at –20 °C; repeated freeze/thaw cycles should be avoided to preserve activity. Validated applications on the supplier datasheet include Western blot (WB) and immunohistochemistry (IHC) on paraffin-embedded tissue, with demonstrated performance shown on MCF7 lysates and human breast carcinoma sections, including peptide-blocking controls. The reagent cross-reacts with Human, Mouse, and Rat samples and is intended to detect the endogenous total Estrogen Receptor-α protein in research workflows such as receptor signalling studies, breast cancer model characterisation, and nuclear hormone receptor expression profiling. Pricing for the 50 µL pack is 1365.0 SAR, with lead times of 6–9 business days from the St. Louis, MO dispatch point, and the product is for research use only — not for diagnostic or therapeutic applications.