Anti-ESRRG Antibody

This polyclonal antibody from Antibodies.com targets ESRRG (Estrogen-Related Receptor Gamma), an orphan nuclear receptor that regulates mitochondrial biogenesis, oxidative phosphorylation, and energy metabolism across metabolically active tissues. Raised in rabbit and supplied as an unconjugated 100 µl reagent, it is validated for western blot and immunohistochemistry workflows against human and mouse samples, supporting studies of transcriptional control in cardiac, neuronal, and hepatic systems.

ESRRG acts as a constitutive transcription factor that partners with PGC-1 family coactivators to drive expression of genes involved in fatty acid oxidation, the TCA cycle, and electron transport chain assembly. Researchers rely on Anti-ESRRG Antibody to investigate roles in inner ear hair cell maintenance, hypoxia response, and oncogenic metabolic reprogramming in breast, prostate, and colorectal cancer models, where ESRRG expression frequently correlates with disease progression.

Each lot is affinity purified and quality controlled for specificity. Refrigerated storage is recommended; aliquot to limit freeze-thaw cycles and protect from light to preserve activity for downstream immunodetection applications.