Anti-ESR2 Antibody

A rabbit polyclonal reagent from Antibodies.com, this primary antibody targets Estrogen Receptor Beta (ERβ), a ligand-activated nuclear receptor that mediates estrogen signaling across reproductive, neural, and cardiovascular tissues. Supplied as 100 µl of unconjugated antiserum, it supports Western blot and immunohistochemistry workflows on human samples, where it can be paired with HRP- or fluorophore-conjugated secondary reagents for chromogenic or fluorescent visualization.

ESR2 (also designated NR3A2) is widely investigated in breast, ovarian, and prostate cancer research, alongside studies of neuroprotection and metabolic regulation. The polyclonal host response enables recognition of multiple epitopes on the receptor, which can be advantageous when probing for splice variants or post-translationally modified forms. Researchers apply this reagent to map receptor distribution in fixed tissue sections and to confirm band identity in lysate-based assays, where complementary secondary antibodies facilitate clean signal development across a range of experimental designs.