Anti-ESR1 Antibody

Polyclonal reagent from Antibodies.com raised in rabbit targets ESR1 (estrogen receptor alpha, ERα), the nuclear hormone receptor that drives estrogen-dependent transcription. The IgG preparation is supplied unconjugated at 50 µl volume and is validated for Western blot and immunohistochemistry across human, mouse, and rat samples, supporting studies of receptor expression, nuclear translocation, and downstream gene activation in breast cancer biology, reproductive endocrinology, and metabolic disease models.

Affinity purification against the recombinant human ESR1 immunogen yields batch-to-batch consistency for detecting the full-length receptor in formalin-fixed tissue sections and in cell or tissue lysates. The unconjugated format pairs with HRP-conjugated or fluorophore-conjugated secondary antibodies in chromogenic and immunofluorescence pipelines, enabling flexible assay design. Recommended storage is at -20 °C, ideally in working aliquots to preserve activity across repeated freeze-thaw cycles. Intended for research use only.