Anti-ESPL1 Antibody

Raised in rabbit against the separase protein, this polyclonal reagent from Antibodies.com targets human ESPL1, the cysteine protease that cleaves the cohesin complex at the metaphase-to-anaphase transition to release sister chromatids. Provided as 100 µl of unconjugated antisera, the antibody is validated for western blot and immunohistochemistry on human samples, supporting studies of mitotic chromosome segregation, cell-cycle checkpoint control, and separase dysfunction in aneuploidy and tumor progression. The reagent pairs cleanly with HRP- or fluorophore-conjugated secondary antibodies and is supplied as a ready-to-titer liquid in a single-use vial format suited to small-scale immunoblot and IHC workflows.