Anti-ESD Antibody

This rabbit polyclonal reagent from Antibodies.com is raised against esterase D (ESD), a cytoplasmic S-formylglutathione hydrolase that participates in formaldehyde detoxification. The unconjugated antibody is supplied as a 100 µl liquid aliquot at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, ready for direct conjugation with secondary detection reagents in Western blot and immunohistochemistry workflows. Validated reactivity spans human and mouse samples, enabling studies that probe ESD expression across mammalian tissues, including tumor biopsies in which ESD levels have been examined as a marker of metabolic and detoxification pathways. Researchers apply this preparation to investigate formaldehyde-processing capacity in cell lysates by Western blot and to localize ESD in fixed tissue sections by IHC, where its cytoplasmic distribution provides a clear signal in epithelial and stromal compartments.