Anti-ERK 1 / 2 Antibody

Produced in rabbit against ERK1, this polyclonal reagent from Antibodies.com recognizes both ERK1 and ERK2 isoforms, supporting studies of the MAPK/ERK signal transduction cascade. The unconjugated IgG is supplied as a 100 µl vial and is validated for Western blot, immunofluorescence, and ELISA workflows. It detects endogenous levels of ERK1 (~44 kDa) and ERK2 (~42 kDa) in human, mouse, and rat samples, which makes it broadly useful for growth factor signaling research, cell proliferation assays, neuronal plasticity studies, and investigations of BRAF or MEK pathway inhibitors. For reliable performance, store the antibody at -20 °C in working aliquots to limit freeze-thaw cycles and protect the reagent from light. The polyclonal host response increases the chance of binding conserved epitopes on both isoforms, which is helpful when comparing basal versus stimulated ERK activation states across tissues or experimental conditions.