Anti-ERG Antibody

The Antibodies.com polyclonal reagent targets the ERG transcription factor, a member of the ETS family that plays a central role in vasculogenesis, angiogenesis, and endothelial cell identity. Produced in rabbit, this unconjugated antibody recognizes the human ERG protein and is validated for Western blot and immunofluorescence workflows, making it useful for studies of vascular biology, prostate cancer (where TMPRSS2-ERG gene fusions are a hallmark molecular event), and hematopoietic research. The reagent is supplied as 100 µl of polyclonal antiserum and binds ERG in both native conformation and denatured samples separated by SDS-PAGE. Researchers commonly apply it to characterize ERG expression in cultured endothelial cells, formalin-fixed tissue sections, and lysates from prostate carcinoma cell lines. The unconjugated format offers flexibility for downstream labeling with custom fluorophores, HRP, or biotin, depending on the experimental design. As a primary antibody from Antibodies.com, it supports clear signal development across standard immunodetection protocols without the need for additional purification steps before use.