Anti-ERCC6 Antibody

The ERCC6 protein, also called CSB, is the ATP-dependent DNA repair factor that activates transcription-coupled nucleotide excision repair and whose loss-of-function mutations cause Cockayne syndrome type B. This rabbit polyclonal antibody from Antibodies.com is raised against ERCC6 and is supplied as 100 µl of unconjugated reagent for Western blot, immunohistochemistry, and immunofluorescence work on human cells and tissue. Researchers use it to probe UV-induced DNA damage response, chromatin remodeling at stalled RNA polymerase II, and ERCC6 expression in patient-derived cell lines and archival sections, often alongside CSA/ERCC8 partners in the TC-NER pathway.