Anti-ERCC6 Antibody

Raised in a rabbit host, this polyclonal Primary Antibody from Antibodies.com binds ERCC6, also known as CSB (Cockayne Syndrome protein B), the ATP-dependent DNA helicase that drives transcription-coupled nucleotide excision repair (TC-NER) by displacing stalled RNA polymerase II from lesion-arrested chromatin.

Validated for Western blot work across human, mouse, and rat lysates, the unconjugated reagent is supplied at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.3. Each vial delivers 100 µl of antibody, leaving secondary reagent and detection chemistry flexible for chemiluminescent, fluorescent, or other downstream workflows.

Investigators working on UV-induced DNA damage response, Cockayne syndrome type B pathology, age-related neurodegeneration, and chromatin-residing transcription recovery assays will find this reagent directly applicable to their research.