Anti-ERBB3 Antibody

The ERBB3 receptor (also called HER3) is a member of the EGFR/ErbB family of receptor tyrosine kinases and plays a central role in signaling pathways that govern cell proliferation, survival, and differentiation. This rabbit polyclonal IgG antibody from Antibodies.com is raised against ERBB3 and is validated for Western blot and immunohistochemistry applications. It detects the human, mouse, and rat protein in tissue and cell lysate samples, supplied as a 200 µL aliquot of unconjugated antibody suitable for standard immunodetection protocols. Researchers studying HER2/ERBB3 heterodimerization, resistance mechanisms in HER2-positive breast cancer, or ErbB family signaling in development and oncology use polyclonal antibodies like this one to probe expression patterns across multiple species. The polyclonal format offers broader epitope coverage than monoclonal reagents, which can be advantageous when detecting ERBB3 splice variants or post-translational modifications.