Anti-ERBB2 (phospho Y1248) Antibody

Phospho-specific polyclonal antibody targeting the Y1248 residue of ERBB2, raised in rabbit and provided by Antibodies.com as an unconjugated IgG preparation validated for Western Blot detection of the human receptor. Y1248 lies within the C-terminal regulatory domain of HER2/ERBB2 and is one of the major receptor autophosphorylation sites used as a readout of kinase activation and downstream signaling. Researchers studying HER2-driven oncology, breast cancer pathways, and receptor tyrosine kinase activation can use this reagent to monitor ligand-dependent or ligand-independent ERBB2 phosphorylation in human cell lysates and tissue-derived samples. The 100 µl single-use vial format is intended for research use only and is compatible with standard immunoblotting workflows, including secondary antibody detection and phospho-specific signal comparison across treated and untreated conditions.