Anti-ErbB2/HER2 (I682) Antibody

ErbB2 (also known as HER2, Neu, or CD340) is a 185 kDa receptor tyrosine kinase of the ErbB family that drives proliferative signaling when amplified or overexpressed, most notably in a subset of breast and gastric carcinomas. This rabbit polyclonal reagent from Antibodies.com corresponds to the I682 designation and is supplied at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2. The unconjugated antibody is validated for Western blot and immunohistochemistry on human, mouse, and rat samples, supporting receptor expression profiling, tumor tissue screening, and downstream signaling studies. The 50 µl vial covers multiple blots and staining runs; refrigerate in the original vial to preserve activity, and prepare small aliquots to limit freeze-thaw cycles when used over an extended period.