Anti-ERBB2 Antibody

The ERBB2 receptor (also known as HER2/neu) is a 185 kDa transmembrane tyrosine kinase of the EGFR family, frequently amplified in breast and gastric carcinomas. This rabbit polyclonal IgG antibody from Antibodies.com targets the C-terminal region of human ERBB2 and cross-reacts with mouse and rat orthologs, supporting translational studies across species.

Validated for Western blot and immunohistochemistry, the reagent produces a characteristic band near 185 kDa on lysates from HER2-amplified cell lines and delivers membranous staining in formalin-fixed tissue sections. The unconjugated format lets researchers pair it with their own HRP or fluorescent secondary reagents. Each vial contains 50 µl of antibody; for long-term use, store at -20°C in small aliquots to limit freeze-thaw cycles and preserve binding reactivity.