Anti-EPXH2 Antibody

The soluble epoxide hydrolase enzyme encoded by the EPHX2 gene — commonly tracked in the literature as EPXH2 or sEH — catalyzes the hydrolysis of epoxyeicosatrienoic acids (EETs) into dihydroxyeicosatrienoic acids (DHETs), a reaction that modulates vascular tone, inflammatory cascades, and blood pressure homeostasis. This rabbit polyclonal reagent from Antibodies.com was raised against EPXH2 and is validated for Western blot and immunohistochemistry workflows, providing clear detection across human, mouse, and rat samples.

Because the antibody is supplied unconjugated, investigators retain full flexibility to pair it with HRP, biotin, or fluorophore-conjugated secondary reagents that match their preferred detection chemistry. Each vial contains 100 µl of polyclonal antiserum, sufficient to support multiple Western blot membranes or a series of immunohistochemistry staining runs on fixed tissue sections.

Key features:

• Host species: Rabbit polyclonal
• Reactivity: Human, Mouse, Rat
• Applications: Western blot (WB), Immunohistochemistry (IHC)
• Conjugate: Unconjugated
• Volume: 100 µl

Researchers working in cardiovascular biology, renal physiology, neuroinflammation, or xenobiotic metabolism will find this reagent useful for characterizing endogenous EPXH2 expression and subcellular localization in disease models, including studies probing the role of soluble epoxide hydrolase in hypertension, atherosclerosis, and ischemia-reperfusion injury. The cross-species reactivity streamlines translational comparisons between rodent experimental systems and human tissue specimens.