Anti-EPS15L1 Antibody

Raised in rabbits, this unconjugated polyclonal antibody from Antibodies.com targets the EPS15L1 protein, a cytoplasmic substrate involved in clathrin-mediated endocytosis and EGFR trafficking. The reagent is validated for Western blot and immunohistochemistry workflows on human samples, supplied as 100 µl of antiserum for research use only. Endogenous EPS15L1 localizes to coated pits and vesicles, where it coordinates cargo selection and internalization through its EH-domain interactions with partners such as epsin and adaptin complexes. The antibody detects the human antigen in cell lysates and fixed tissue sections, supporting studies of receptor down-regulation, synaptic vesicle recycling, and membrane trafficking. Host species is Rabbit, with reactivity restricted to human tissue, and the unconjugated format allows flexible secondary labeling in custom detection assays such as chromogenic or fluorescent IHC and standard immunoblotting.