Anti-EPM2A Antibody

For researchers investigating Lafora disease and glycogen metabolism, this rabbit polyclonal antibody from Antibodies.com specifically recognizes EPM2A (laforin), a dual-specificity glucan phosphatase implicated in progressive myoclonus epilepsy. The unconjugated reagent is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a 100 µl vial, and has been validated for Western blot and immunohistochemistry workflows across human, mouse, and rat sample types. Laforin plays a central role in regulating glycogen chain length and preventing the accumulation of hyperphosphorylated, insoluble polyglucosan inclusions that define Lafora bodies, making reliable detection essential for studies of disease pathogenesis and therapeutic development.