Anti-EphA2 Antibody

This rabbit polyclonal antibody from Antibodies.com targets EphA2 (Erythropoietin-producing hepatocellular receptor A2), a receptor tyrosine kinase implicated in cell migration, angiogenesis, and tumor progression. The unconjugated antibody is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, packaged in a 100 µl vial.

Validated applications include western blot and immunohistochemistry on Human, Mouse, and Rat samples. EphA2 is frequently overexpressed in breast carcinoma, non-small cell lung cancer, prostate adenocarcinoma, ovarian cancer, melanoma, and glioblastoma, making this reagent relevant to cancer biology, receptor signaling studies, and investigations of ephrin-A ligand interactions.

For optimal stability, aliquot the antibody and store at -20°C, avoiding repeated freeze-thaw cycles. The polyclonal format yields recognition of multiple epitopes on the EphA2 protein, useful when working with post-translationally modified or mutated variants of the receptor. Researchers studying receptor tyrosine kinase signaling, ephrin pathway biology, or tumor microenvironment interactions will find this a practical tool for both immunoblotting and tissue-section staining workflows.