Anti-EPHA2 Antibody

This unconjugated polyclonal reagent from Antibodies.com targets Ephrin type-A receptor 2 (EPHA2), a transmembrane receptor tyrosine kinase implicated in developmental patterning, vascular remodeling, and oncogenic signaling. Raised in rabbit, the antibody is supplied as 200 µl of IgG in a single-use vial and is validated for Western blotting, immunohistochemistry, and flow cytometry workflows. Cross-reactivity studies indicate detection of both human and mouse EPHA2, supporting translational projects that compare orthologous tissue samples or xenograft models. The unconjugated format allows flexible pairing with secondary labels of the researcher's choice, including HRP, biotin, or fluorochrome conjugates, depending on the detection platform. EPHA2 is commonly examined in studies of breast carcinoma, prostate cancer, glioblastoma, and lens epithelial biology, where altered receptor expression or ligand-induced phosphorylation serves as a focal readout. Researchers investigating ephrin-mediated contact inhibition, tumor angiogenesis, or metastatic dissemination can apply this reagent for mapping receptor distribution across cultured cell lines and primary specimens. Short-term storage at 4 °C preserves antibody activity for routine use, while small aliquots help avoid repeated freeze-thaw cycles that can degrade polyclonal titer. The IgG isotype and rabbit host background make it compatible with the broad range of anti-rabbit secondary reagents stocked in most immunology laboratories.