Anti-EPC1 Antibody

This rabbit-derived polyclonal reagent targets EPC1 (Enhancer of Polycomb Homolog 1), a chromatin-associated nuclear protein implicated in histone acetylation, transcriptional silencing, and DNA damage response pathways. Supplied as 100 µl of unconjugated antiserum, the antibody is validated for western blot (WB) and immunofluorescence (IF) workflows and cross-reacts with both human and mouse samples, supporting comparative studies across cultured cell lines and primary tissue.

The IgG fraction was raised against a recombinant region of EPC1 and affinity-purified to minimize nonspecific background. Because EPC1 participates in Polycomb-repressive complex remodeling at H3K27-methylated loci, the reagent is well suited to mapping enhancer-of-polycomb occupancy by IF imaging and to tracking endogenous EPC1 protein levels by WB under perturbation conditions, including RNAi knockdown and small-molecule inhibition of histone-modifying enzymes.

Provided by Antibodies.com as a ready-to-use vial, this primary antibody is recommended for researchers investigating epigenetic regulation, chromatin remodeling, and the interface between transcription and DNA repair in mammalian systems.