Anti-EPAS-1 Antibody

The Antibodies.com catalogue lists this rabbit polyclonal reagent raised against EPAS-1, the endothelial PAS domain-containing protein 1 also known as HIF-2α. EPAS-1 functions as a hypoxia-inducible transcription factor that heterodimerises with ARNT and drives expression of genes controlling angiogenesis, erythropoietin production, and metabolic adaptation under low oxygen tension. The antibody is supplied as an unconjugated IgG preparation at 100 µl per vial and is validated for western blot and ELISA workflows using human, mouse, and rat samples. Investigators examining HIF pathway cross-talk, renal and hepatic erythropoietin regulation, and tumour microenvironment hypoxia depend on this reagent for protein-level detection of the HIF-2α subunit in basic research settings.