Anti-ENTPD3 Antibody

ENTPD3 (Ectonucleoside Triphosphate Diphosphohydrolase 3) is an ectonucleotidase that hydrolyzes extracellular ATP and ADP, modulating purinergic signaling at the cell surface. This rabbit polyclonal antibody from Antibodies.com targets the human ENTPD3 protein and is supplied as 100 µL of unconjugated antiserum intended for Western blot and immunohistochemistry workflows.

The reagent detects endogenous ENTPD3, a membrane-bound enzyme of roughly 70 kDa expressed most strongly in cerebellar and hippocampal neurons, with additional staining observed in pancreatic islet beta cells. Validated applications include immunoblotting of human cell lysates and immunohistochemical localization in formalin-fixed, paraffin-embedded tissue sections.

The polyclonal format offers broad epitope recognition, useful for detecting both linear and conformational determinants of the target. The vial should be stored refrigerated for short-term use; for extended storage, aliquot and freeze at -20°C, avoiding repeated freeze-thaw cycles to maintain antibody performance across multiple experiments.