Anti-ENTPD3 Antibody

This unconjugated rabbit polyclonal IgG reagent from Antibodies.com recognizes ENTPD3, a glycosylated plasma-membrane ectonucleoside triphosphate diphosphohydrolase expressed primarily on pancreatic islet beta cells and on selected neuronal populations. The enzyme hydrolyzes extracellular nucleoside triphosphates and diphosphates, shaping local purinergic signaling and contributing to the regulation of insulin secretion, which makes it a marker of interest in studies of islet biology and metabolic signaling. Supplied as 100 µl of polyclonal antibody in an unconjugated format, the preparation is validated for Western blot detection of the human, mouse, and rat proteins. The polyclonal response broadens epitope coverage across the target relative to a monoclonal reagent, while the IgG isotype allows flexible pairing with standard HRP, fluorophore, or biotin-conjugated secondary detection systems in immunoblotting workflows. Researchers examining islet cell physiology, NTPDase-family expression profiling, or purinergic pathways in tissue lysates can use this reagent to probe ENTPD3 abundance across human, mouse, and rat samples run on standard reducing SDS-PAGE gels. The unconjugated format leaves reporter chemistry, dilution, and blocking strategy entirely under the end user's control.