Anti-ENTPD2 Antibody

Rabbit polyclonal antibody raised against human ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2, also known as CD39L1), distributed by Antibodies.com as an unconjugated reagent in a 100 µL volume. ENTPD2 is a glycosylated, membrane-bound ectonucleotidase that hydrolyzes extracellular ATP and ADP to AMP, shaping purinergic signaling on vascular endothelium, including liver sinusoidal endothelial cells, and contributing to extracellular adenosine accumulation within the tumor microenvironment.

Produced in rabbit as a polyclonal reagent, the antibody is validated for Western blot (WB) and immunofluorescence (IF) applications on human samples. Supplied without a fluorophore or enzyme conjugate, the reagent offers flexibility in secondary antibody selection and downstream chromogenic, fluorescent, or custom labeling workflows. Researchers investigating purinergic signaling, hepatic vascular biology, inflammation, and tumor immune evasion commonly use unconjugated rabbit polyclonals such as this one to detect endogenous ENTPD2 expression in both whole-cell lysates and fixed-cell imaging preparations.

For handling, aliquot upon first use to limit repeated freeze-thaw cycles, keep refrigerated for short-term storage, and store frozen for longer-term stability. Protect from light when paired with fluorescence-based secondary detection. Intended for research use only; not validated for diagnostic or therapeutic applications.