Anti-ENPP7 Antibody

Raised in rabbits and supplied as a polyclonal IgG preparation, this unconjugated reagent targets ENPP7 (Ectonucleotide pyrophosphatase/phosphodiesterase 7), an intestinal membrane-bound enzyme commonly referred to as alkaline sphingomyelinase that hydrolyzes sphingomyelin to generate ceramide.

From Antibodies.com, the antibody is validated for Western blot (WB) detection of the human ENPP7 protein, supporting research into sphingolipid digestion, mucosal lipid signaling, and gastrointestinal physiology. The polyclonal format recognizes multiple epitopes on the target, a useful property when probing endogenous expression in cell or tissue lysates where a single monoclonal epitope may be compromised by denaturation.

Each vial is supplied at 200 µl volume; store aliquots at -20°C and avoid repeated freeze-thaw cycles to preserve binding activity. For Western blot, dilute in blocking buffer appropriate to your secondary detection system and include positive and negative lysate controls to confirm specificity.