Anti-ENPP7 Antibody

This rabbit polyclonal antibody targets human ENPP7 (ectonucleotide pyrophosphatase/phosphodiesterase family member 7), an intestinal alkaline sphingomyelinase that hydrolyzes sphingomyelin in the gut lumen and contributes to dietary lipid handling and mucosal homeostasis. The reagent is supplied by Antibodies.com as a 100 µL liquid aliquot of whole IgG raised in rabbit, unconjugated, and intended for Western blot detection of the ENPP7 polypeptide in research samples.

ENPP7 expression is predominantly intestinal, and altered sphingomyelinase activity has been reported in inflammatory bowel disease, colorectal adenoma tissue, and select metabolic disorders, making this marker relevant to studies of gut lipid metabolism, epithelial differentiation, and gastrointestinal pathophysiology. As a polyclonal reagent, the antibody recognizes multiple epitopes on the human ENPP7 protein, supporting visualization of the full-length target in tissue lysates and cultured cell lines under denaturing, reducing conditions typical of SDS-PAGE Western blot workflows.

The vial should be stored refrigerated, and small working aliquots are recommended to limit repeated freeze-thaw cycles that can erode polyclonal activity over time. Provided as a single-use research reagent, this product from Antibodies.com is suited for investigators studying sphingomyelinase biology, intestinal alkaline phosphatase-related pathways, or comparative expression of ENPP7 between normal and diseased gastrointestinal mucosa. For research use only.