Anti-Endothelin 1 Antibody

Affinity-purified polyclonal reagent for detecting human Endothelin 1 (ET-1), a 21-amino acid vasoactive peptide encoded by the EDN1 gene and implicated in vascular tone regulation, pulmonary hypertension, and tumor microenvironment signaling. Raised in rabbit, the unconjugated format allows flexible pairing with user-selected reporter-labeled secondary antibodies in custom detection workflows. The 100 µl volume supports multi-experiment use, and aliquoting upon first thaw preserves reagent activity across extended projects. Validated for Western blot and immunofluorescence on human samples, the antibody recognizes multiple epitopes across the mature peptide, supporting consistent detection across varied sample preparations including cultured endothelial cells and tissue sections. Store at -20 °C in working aliquots to limit freeze-thaw cycles, and avoid prolonged exposure to room temperature. Intended applications include cardiovascular biology studies of the endothelin axis, characterization of endothelial cell signaling, and oncology research where ET-1 expression patterns are being mapped.

Supplied by Antibodies.com as a primary antibody reagent intended for research use only.