Anti-Endostatin Antibody [KT60]

The Anti-Endostatin Antibody [KT60] from Antibodies.com is a research-grade mouse monoclonal antibody that recognizes endostatin, the C-terminal ~20 kDa proteolytic fragment of collagen XVIII (COL18A1). Endostatin functions as a potent endogenous angiogenesis inhibitor and is studied extensively in tumor biology, wound healing, and vascular research, where it suppresses endothelial cell proliferation and new vessel formation. This unconjugated IgG2a reagent is supplied as a 100 ug liquid aliquot and is validated for ELISA and Western blot against human endostatin, supporting quantification in conditioned media, cell culture supernatants, and tissue lysates. For handling, keep refrigerated and protect from light; aliquot upon arrival to minimize freeze-thaw cycles and preserve activity over the product shelf life. The KT60 clone is frequently used to probe angiogenic balance, anti-angiogenic therapy response, and basement membrane remodeling in cancer and fibrosis models.