Anti-Endo180 Antibody

Primary antibody for studying Endo180 (also known as MRC2, uPARAP, or CD280), a type I transmembrane receptor of the mannose receptor family that mediates collagen internalization and turnover. Raised in Rabbit and supplied by Antibodies.com as an unconjugated polyclonal reagent of 100 µl, this antibody is validated for western blot and ELISA workflows across Human, Mouse, and Rat samples.

Endo180 is widely investigated in the context of extracellular matrix remodeling, fibroblast-mediated tissue repair, osteoclast-driven bone resorption, and the invasive behavior of carcinoma and melanoma cells. Researchers working on fibrosis, atherosclerosis, tumor-stroma interactions, or matrix biology use this reagent to track receptor expression, ligand uptake, and downstream signaling in cell culture lysates and primary tissue.

The polyclonal format provides recognition of multiple epitopes on the MRC2 extracellular domain, supporting reproducible detection in immunoblotting and antigen-down ELISA assays where conformational sensitivity matters.