Anti-EMR2 Antibody

A polyclonal reagent from Antibodies.com targets EMR2 (also known as CD312 or ADGRE2), an adhesion-class G protein-coupled receptor expressed on human myeloid lineage cells including monocytes, macrophages, neutrophils, and dendritic cells. The antibody is raised in rabbit, supplied unconjugated in a 100 µl volume, and validated for Western blot and ELISA workflows against human samples. EMR2 mediates cell-cell and cell-matrix interactions through binding of chondroitin sulfate glycosaminoglycans, making antibodies to this receptor useful for studies of leukocyte adhesion, migration, and innate immune activation. Researchers investigating CD312 expression on granulocyte populations, or screening for mutations linked to vibratory urticaria, can use this reagent to probe native protein in cell lysates and recombinant preparations. As an unconjugated format, it is suited to custom labeling schemes with HRP, biotin, or fluorophore conjugates depending on the downstream detection method.