Anti-EMR2 Antibody

This rabbit polyclonal reagent from Antibodies.com targets EMR2, an adhesion-class G protein-coupled receptor also referenced as CD312 and ADGRE2. The protein is expressed on myeloid lineage cells including macrophages, dendritic cells, and granulocytes, where it contributes to cell adhesion, chemotaxis, and inflammatory signaling cascades relevant to leukocyte trafficking and tissue-resident immune responses.

Supplied as 100 µl of a 1 mg/ml stock in phosphate buffered saline (PBS) containing 15 mM sodium azide at approximately pH 7.2, the unconjugated antibody is validated for Western blot workflows and cross-reacts with Human, Mouse, and Rat EMR2. The polyclonal format allows recognition of multiple epitopes across the EMR2 extracellular region, supporting studies that compare protein expression across species or examine post-translational processing in immune cell populations.

For optimal stability, aliquot the antibody upon first use to limit freeze-thaw cycles and store refrigerated in the dark. Researchers studying macrophage polarization, neutrophil migration, or inflammatory receptor signaling will find this reagent applicable to lysate-based detection of EMR2 expression across a range of experimental systems.