Anti-EME2 Antibody

Developed as a polyclonal IgG reagent in rabbit and supplied as an unconjugated 50 µl aliquot, this Antibodies.com antibody is raised against EME2, a member of the XPF/MUS81 family of structure-specific endonucleases with roles in homologous recombination and the cellular DNA damage response. Because EME2 participates in pathways relevant to genome maintenance, this reagent supports laboratories investigating repair factor expression and meiotic or somatic recombination mechanisms in human systems.

Validated for Western blot detection in human samples, the unconjugated format lets researchers pair the reagent with a secondary antibody of their choice for chemiluminescent or fluorescent readouts. The polyclonal composition provides broad epitope coverage across full-length EME2 isoforms, supporting immunoblotting of whole-cell and nuclear extracts, verification of expression in knockdown or knockout cell line models, and time-course analysis following genotoxic insult.

For routine use, store refrigerated at standard antibody handling temperatures, aliquot upon first thaw to limit repeated freeze-thaw cycles, and protect from light where applicable to preserve activity over the shelf life of the product. The rabbit host species and IgG isotype also make this reagent compatible with common anti-rabbit secondary antibodies used in standard immunoblotting workflows.