Anti-EME2 Antibody

Produced by Antibodies.com as a rabbit polyclonal reagent, this antibody recognizes human EME2 (Essential Meiotic Endonuclease 2), a structure-selective DNA endonuclease that partners with MUS81 to cleave branched DNA intermediates during homologous recombination repair and meiotic recombination. The unconjugated IgG preparation is supplied in a 200 µl vial and validated for Western Blot applications.

EME2 contributes to genome maintenance through its role in resolving Holliday junctions, replication fork structures, and other DNA substrates that arise during the DNA damage response and crossover formation. Researchers investigating chromosome segregation, fertility biology, and DNA repair pathways in mammalian systems can use this antibody to probe endogenous EME2 protein levels in cell lysates. The polyclonal format offers broader epitope coverage than monoclonal alternatives, supporting consistent detection across experimental conditions.