Anti-ELN Antibody

This rabbit polyclonal antibody from Antibodies.com targets elastin (ELN), the extracellular matrix protein responsible for the elastic recoil of arteries, lung parenchyma, skin, and other elastic connective tissues. Raised in rabbit and supplied as an unconjugated reagent in a 100 µl volume, the antibody is intended for Western blot and immunohistochemistry workflows on human samples, making it a useful tool for studies of vascular biology, fibrotic tissue remodeling, and dermal aging research. The polyclonal format provides recognition of multiple elastin epitopes, which is particularly valuable when probing processed or cross-linked elastin fragments generated by matrix metalloproteinase activity. Researchers investigating connective tissue disorders such as cutis laxa, supravalvular aortic stenosis, Williams-Beuren syndrome, or age-related elastic fiber degradation will find this reagent suited to detecting full-length tropoelastin in lysates as well as mature elastin incorporated into formalin-fixed tissue sections. Refrigerated storage is recommended, with aliquoting used to limit freeze-thaw cycles and preserve antibody titer for repeated blotting experiments.