Anti-ELMO1 Antibody

ELMO1 (Engulfment and Cell Motility protein 1) is a cytoplasmic scaffolding protein that partners with Dock180 to form a bipartite guanine nucleotide exchange factor complex for the small GTPase Rac1, driving actin cytoskeleton remodeling at the leading edge of migrating cells. This rabbit polyclonal reagent from Antibodies.com was raised against ELMO1 and validated for Western blot detection across human, mouse, and rat samples.

The unconjugated IgG is supplied at 1 mg/mL in PBS containing 0.1% sodium azide and 50% glycerol as a cryoprotectant, shipped as a 100 µl vial that is convenient for extended bench use. Researchers studying cancer cell invasion, leukocyte chemotaxis, phagocytic clearance of apoptotic debris, integrin signaling, or models of diabetic nephropathy will find this antibody useful for probing endogenous ELMO1 expression in whole-cell lysates.

Store the vial at -20 °C in working aliquots to limit freeze-thaw cycles, and protect from light during handling.