Anti-Elk1 (Ab-389) Antibody

This polyclonal antibody from Antibodies.com is raised in rabbit against the transcription factor Elk1, a downstream effector of the ERK/MAPK signaling cascade. The reagent ships as 100 µl of unconjugated antiserum and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows using Human, Mouse, and Rat samples.

Elk1 (Ets-like protein 1) belongs to the ternary complex factor family and drives immediate-early gene expression in response to growth factor and cellular stress stimuli. The Ab-389 designation indicates reactivity centered on residue 389 of Elk1, a region that harbors ERK/MAPK phosphoacceptor sites commonly monitored to follow pathway activation. Laboratories investigating neuronal plasticity, oncogenic Ras/MAPK signaling, and stimulus-dependent transcriptional responses rely on this reagent for research use only.

Supplied in a single-use vial, the antibody is stored refrigerated at 4 °C to preserve activity, and short-term handling on ice is advised for immunofluorescence protocols to limit freeze-thaw cycles and protect from light during incubations.