Anti-ELAV2 / 4 Antibody

This rabbit polyclonal reagent from Antibodies.com is raised against the ELAV2 (also known as HuB) RNA-binding protein, with reported cross-recognition of the closely related family member ELAV4 (HuD). The antibody is supplied as 100 µl of unconjugated antiserum in a vial format suited to western blot (WB) and immunofluorescence (IF) workflows.

Validated reactivity covers human, mouse, and rat samples, allowing detection of the target in lysates and tissue sections from these species. ELAV2/HuB is a neuronal RNA-binding protein involved in post-transcriptional regulation, mRNA stability, and neuronal differentiation, making this reagent useful for studies of nervous system development, RNA processing, and paraneoplastic neurological syndromes where anti-Hu autoantibodies are clinically relevant.

As a polyclonal, the reagent recognizes multiple epitopes on the target, which can improve signal on WB membranes and in IF staining of cultured cells or brain tissue. The unconjugated format gives users flexibility to couple the antibody to fluorophores, HRP, or biotin depending on the downstream assay.