Anti-ELAC2 Antibody

ELAC2 is a mitochondrial zinc phosphodiesterase best known for trimming the 3' trailer of precursor tRNAs and for maturing mitochondrial transcripts, and the unconjugated rabbit polyclonal reagent from Antibodies.com lets researchers visualise this protein across Western blot, immunohistochemistry, and immunofluorescence workflows on human material. Supplied as 100 µl of IgG at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody is intended for laboratory research into prostate cancer biology (ELAC2 was originally mapped as the HPC2 susceptibility locus), mitochondrial RNA processing, and rare ELAC2-linked conditions such as combined oxidative phosphorylation deficiency 17. The polyclonal format offers broader epitope coverage than a monoclonal, which is helpful when working with formalin-fixed sections where antigen masking reduces the number of accessible sites. Aliquot the glycerol-stabilised buffer into working volumes on arrival and store at -20°C; the cryoprotectant guards the protein during freezing but repeated freeze-thaw cycles should still be avoided, and the sodium azide is incompatible with live-cell workflows or HRP-conjugated secondary systems that are azide-sensitive. For research use only.