Anti-EIF6 Antibody

This polyclonal rabbit antibody targets EIF6 (eukaryotic translation initiation factor 6), a highly conserved protein that binds the 60S ribosomal subunit and regulates ribosome biogenesis by preventing premature 60S/40S subunit joining. Dysregulated EIF6 expression has been linked to altered translational control in rapidly dividing cells and several cancer contexts, making it a useful reagent for studies of ribosome assembly, protein synthesis, and growth signaling pathways.

From Antibodies.com, this reagent is supplied as an unconjugated polyclonal antibody raised in rabbit and validated for western blot, immunohistochemistry, and immunofluorescence workflows. The antibody cross-reacts with human, mouse, and rat EIF6, enabling consistent detection across standard mammalian model systems and matched human tissue samples without needing separate primary reagents for each species.

The product ships in a 100 µl vial of liquid antiserum. For routine use, refrigerate the vial at 4 °C; for longer projects, aliquot and freeze at -20 °C to limit freeze-thaw damage and preserve antigen-binding activity. The unconjugated format allows the antibody to be paired with any preferred secondary detection reagent, including HRP conjugates for chromogenic western blot, fluorescent dyes for immunofluorescence imaging, or biotin-streptavidin systems for immunohistochemistry amplification.