Anti-EIF4G1 (phospho S1232) Antibody

Phosphorylation of EIF4G1 at serine 1232 is one of several post-translational marks that regulate cap-dependent translation initiation, and this rabbit polyclonal antibody from Antibodies.com is raised specifically against this phospho-epitope on the EIF4G1 scaffold protein. Supplied as 200 µL of unconjugated IgG, the reagent is validated for Western blot and immunohistochemistry on human samples and is intended for research use only.

Because EIF4G1 forms part of the eIF4F initiation complex, an antibody that targets the S1232-phosphorylated form is used to monitor signaling through translation-controlling pathways, including the mTOR axis, in cell growth, stress response, and tumor biology work. The polyclonal rabbit host and unconjugated IgG format support chromogenic, fluorescent, or chemiluminescent detection once a labeled secondary is added, and they leave the reagent open to custom conjugation for microscopy or bead-based pull-down experiments.

Brief handling notes: keep the liquid antibody refrigerated for routine use, and aliquot if repeated freeze-thaw cycles are anticipated across extended studies.