Anti-EIF4B Antibody

The Anti-EIF4B Antibody from Antibodies.com is a rabbit polyclonal reagent raised against eukaryotic translation initiation factor 4B, a key regulator of cap-dependent mRNA translation. EIF4B is phosphorylated downstream of S6 kinase and mTOR signaling and cooperates with EIF4A to unwind secondary structure in the 5' untranslated region of target transcripts, making it a useful marker in studies of translational control, oncogenic signaling, and stress responses. The unconjugated antibody is supplied as 100 µl of reagent and has been validated for western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples. The polyclonal format provides broad epitope recognition, supporting consistent detection in cancer cell lines, neural tissue, and translation-focused biochemical assays where monoclonal antibodies may miss post-translationally modified or splice-variant forms of the target. Researchers commonly pair this reagent with standard laboratory buffers, methanol or paraformaldehyde fixation protocols, and HRP- or fluorophore-conjugated secondary antibodies for chromogenic or fluorescence-based readouts. Intended for research use only, the antibody is suited to academic and pharmaceutical studies examining how altered EIF4B expression contributes to tumorigenesis, metabolic reprogramming, and neuronal function.