Anti-EIF4B Antibody

Produced in rabbit as a polyclonal reagent, this Antibodies.com antibody recognizes eukaryotic translation initiation factor 4B (EIF4B), a 69 kDa RNA-binding factor that supports cap-dependent translation and acts as a downstream effector of mTOR/S6K signaling. The unconjugated preparation is supplied as a 50 µl volume at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, ready for direct incorporation into western blot, immunohistochemistry, and immunofluorescence protocols. Reactivity has been confirmed against human, mouse, and rat samples, supporting comparative work in cell lines, primary cultures, and rodent tissue models used in cancer biology, neurobiology, and translational regulation studies. The polyclonal pool captures multiple epitopes on the target, which is useful when probing phosphorylated or alternatively processed forms of EIF4B in cap-complex interactome experiments. For best results, store the vial at -20°C in single-use aliquots to minimize freeze-thaw cycles and preserve binding activity over the working life of the reagent.