Anti-EIF3E Antibody

This polyclonal reagent from Antibodies.com targets EIF3E, the p48/INT6 subunit of the eukaryotic translation initiation factor 3 complex. EIF3E participates in cap-dependent translation initiation and has been studied in the context of mTOR signaling, ribosomal scanning, and breast cancer biology, where disruption of the INT6 locus alters cell proliferation.

The antibody is raised in rabbit and supplied as an unconjugated IgG preparation at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial. Validated application coverage includes Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF), with reactivity confirmed against human, mouse, and rat samples.

For handling, store the vial at -20°C in small aliquots to limit freeze-thaw cycles and protect the solution from light; the glycerol content helps prevent freezing at standard laboratory freezer temperatures. Intended for research use only, the reagent supports laboratories investigating translation control, the eIF3 complex, and EIF3E-specific functions in normal and transformed cells.