Anti-eIF2Bdelta Antibody

The eIF2Bdelta subunit is the delta (δ) component of the heteropentameric eukaryotic translation initiation factor 2B (eIF2B) complex, a guanine nucleotide exchange factor that recycles eIF2-GDP to active eIF2-GTP during cap-dependent protein synthesis initiation. Mutations in the EIF2B4 gene that encodes this subunit are linked to leukoencephalopathy with vanishing white matter, making the protein a focus in neurological and translation-regulation studies.

This unconjugated rabbit polyclonal primary antibody from Antibodies.com is supplied as 100 µl of liquid in a single vial and is validated for Western blot (WB) and immunohistochemistry (IHC) detection of human eIF2Bdelta. The polyclonal host response supports recognition of multiple epitopes on the target, useful when probing endogenous expression across cell and tissue lysates. Researchers studying integrated stress response signaling, stress granule biology, and eukaryotic translation control apply this reagent in research use only workflows to characterize abundance and subcellular localization of the delta subunit.