Anti-EID3 Antibody

Produced in rabbit as an unconjugated polyclonal reagent, this Antibodies.com primary antibody recognizes EID3, a member of the EID family of EP300-interacting transcriptional regulators that modulate histone acetyltransferase activity and cellular differentiation programs. The antibody is supplied as 100 µl of liquid and is validated for western blot (WB) and immunohistochemistry (IHC) workflows, supporting detection in both human and mouse sample material. The vial should be refrigerated on arrival; aliquot and freeze for longer storage, avoiding repeated freeze-thaw cycles.

EID3 (also referenced as CRI2 or NS4EB) acts as an inhibitor of differentiation by binding CBP and p300 and blocking acetyltransferase-dependent gene activation, and the protein is expressed in a restricted pattern that includes skeletal muscle progenitors and certain cancer cell lines. Polyclonal antibodies raised against this target typically recognize multiple epitopes, which can be useful when probing truncated splice variants or post-translationally modified forms of EID3 in nuclear extracts.

The unconjugated format leaves the antibody free of fluorophore or enzyme label, letting each laboratory pair it with a secondary detection system matched to their experimental design. Host species is rabbit, clonality is polyclonal, and reactivity has been confirmed for human and mouse. Researchers working on retinoblastoma-associated chromatin complexes, nuclear receptor signaling, and muscle lineage commitment commonly select anti-EID3 reagents as part of co-immunoprecipitation and chromatin-focused studies.