Anti-EHD1 Antibody

This polyclonal antibody from Antibodies.com targets EHD1 (EH Domain Containing 1), a key regulator of endocytic membrane trafficking and receptor recycling in mammalian cells. EHD1 participates in the tubulation and fission of endosomal compartments, coupling cargo sorting with vesicular transport back to the plasma membrane, and it interacts with partner proteins containing EH domains, including Eps15 and intersectin family members.

Raised in rabbit (IgG isotype) and supplied unconjugated at 100 µl per vial, the reagent is validated for Western blot detection of human EHD1 in research lysates. For long-term integrity, store at -20°C and keep working aliquots to avoid repeated freeze-thaw cycles. Investigators apply this antibody to characterize endosomal dynamics, cargo retrieval routes, and the connections between EHD-family proteins and disorders in which receptor trafficking is perturbed, including certain neurodegenerative and metabolic disease models.